BDBM50119471 1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethyl]-4-(2-ethoxy-phenyl)-piperazine::CHEMBL142147

SMILES CCOc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccc(F)cc2)-c2ccc(F)cc2)CC1

InChI Key InChIKey=OUQCDNRPXRIJIM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119471   

Target5-hydroxytryptamine receptor 1A(Rat)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50119471(1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethy...)
Affinity DataIC50: 51.9nMAssay Description:In vitro binding affinity for serotonin 5-hydroxytryptamine 1A receptor fof rat cerebral cortex using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50119471(1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethy...)
Affinity DataIC50: 268nMAssay Description:In vitro binding affinity for Dopamine D2 receptor of rat using [3H]YM-09151 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50119471(1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethy...)
Affinity DataIC50: 273nMAssay Description:In vitro binding affinity for serotonin 5-hydroxytryptamine 2A receptor of rat cerebral cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed