BDBM50119478 1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(3-trifluoromethyl-phenyl)-piperazine::CHEMBL342119

SMILES FC(F)(F)c1cccc(c1)N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1

InChI Key InChIKey=SGAILRJJEWIMSO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119478   

TargetD(2) dopamine receptor(Rat)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50119478(1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(3-trifl...)
Affinity DataIC50: 136nMAssay Description:In vitro binding affinity for Dopamine D2 receptor of rat using [3H]YM-09151 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50119478(1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(3-trifl...)
Affinity DataIC50: 206nMAssay Description:In vitro binding affinity for serotonin 5-hydroxytryptamine 1A receptor fof rat cerebral cortex using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50119478(1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(3-trifl...)
Affinity DataIC50: 2.13E+3nMAssay Description:In vitro binding affinity for serotonin 5-hydroxytryptamine 2A receptor of rat cerebral cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed