BDBM50119691 2-Bromo-1-(4-nitro-phenyl)-ethanone::CHEMBL106072

SMILES [O-][N+](=O)c1ccc(cc1)C(=O)CBr

InChI Key InChIKey=MBUPVGIGAMCMBT-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119691   

TargetGlycogen synthase kinase-3 beta(Human)
Central University

Curated by ChEMBL
LigandPNGBDBM50119691(2-Bromo-1-(4-nitro-phenyl)-ethanone | CHEMBL106072)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of glycogen synthase kinase-3 beta (unknown origin) using GS-1 as substrate after 20 mins by scintillation counting analysis in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Central University

Curated by ChEMBL
LigandPNGBDBM50119691(2-Bromo-1-(4-nitro-phenyl)-ethanone | CHEMBL106072)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GSK3-beta using GS1 as substrate and [gamma-32P]ATP after 20 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50119691(2-Bromo-1-(4-nitro-phenyl)-ethanone | CHEMBL106072)
Affinity DataKi:  1.95E+5nMAssay Description:Dissociation constant towards Protein-tyrosine phosphatase 1B receptor-inhibitor complex was determined using PNP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed