BDBM50119702 CHEMBL102925::N-{(S)-1-[3-(4-Cyclopropanecarbonyl-phenoxy)-propyl]-pyrrolidin-3-yl}-4-ethyl-benzenesulfonamide

SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1

InChI Key InChIKey=JGRFHTWWWXEAHZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119702   

TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119702(N-{(S)-1-[3-(4-Cyclopropanecarbonyl-phenoxy)-propy...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity towards rats Histamine type 3 (H3) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119702(N-{(S)-1-[3-(4-Cyclopropanecarbonyl-phenoxy)-propy...)
Affinity DataKi:  330nMAssay Description:Binding affinity towards human Histamine H2 receptor (For compound 11)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119702(N-{(S)-1-[3-(4-Cyclopropanecarbonyl-phenoxy)-propy...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity to the human Histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed