BDBM50119784 1-[6-(1lambda~5~-pyridin-1-yl)hexyl]-1lambda~5~-pyridine;diiodide::CHEMBL104381::CHEMBL389283

SMILES C(CCC[n+]1ccccc1)CC[n+]1ccccc1

InChI Key InChIKey=WUAWIFPABARFIQ-UHFFFAOYSA-N

Data  5 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50119784   

TargetAcetylcholinesterase(Electric eel)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50119784(CHEMBL104381 | CHEMBL389283 | 1-[6-(1lambda~5~-pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50119784(CHEMBL104381 | CHEMBL389283 | 1-[6-(1lambda~5~-pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Military Health Sciences

Curated by ChEMBL
LigandPNGBDBM50119784(CHEMBL104381 | CHEMBL389283 | 1-[6-(1lambda~5~-pyr...)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Military Health Sciences

Curated by ChEMBL
LigandPNGBDBM50119784(CHEMBL104381 | CHEMBL389283 | 1-[6-(1lambda~5~-pyr...)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of human plasma BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119784(CHEMBL104381 | CHEMBL389283 | 1-[6-(1lambda~5~-pyr...)
Affinity DataKi:  9.78E+4nMAssay Description:Binding affinity for nicotinic acetylcholine receptor alpha4-beta2 was evaluated by its ability to inhibit [3H]NIC binding to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50119784(CHEMBL104381 | CHEMBL389283 | 1-[6-(1lambda~5~-pyr...)
Affinity DataKi:  1.60E+7nMAssay Description:Mixed-type inhibition of electric eel acetylcholinesterase using acetylcholine bromide as substrate assessed as concentration required for 25% inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
TBA

Curated by ChEMBL
LigandPNGBDBM50119784(CHEMBL104381 | CHEMBL389283 | 1-[6-(1lambda~5~-pyr...)
Affinity DataKi:  1.20E+5nMAssay Description:Mixed-type inhibition of horse serum butyrylcholinesterase using acetylcholine bromide as substrate assessed as free enzyme-inhibitor complex by Line...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
TBA

Curated by ChEMBL
LigandPNGBDBM50119784(CHEMBL104381 | CHEMBL389283 | 1-[6-(1lambda~5~-pyr...)
Affinity DataKi:  6.20E+5nMAssay Description:Mixed-type inhibition of horse serum butyrylcholinesterase using acetylcholine bromide as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119784(CHEMBL104381 | CHEMBL389283 | 1-[6-(1lambda~5~-pyr...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity nicotinic acetylcholine receptor alpha-7 was evaluated by its ability to inhibit [3H]methyllycaconitine ([3H]-MLA) binding to rat br...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed