BDBM50120096 4-(2-Chloro-6-methyl-phenylamino)-imidazo[1,5-a]quinoxaline-8-carbonitrile::4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]quinoxaline-8-carbonitrile::CHEMBL423321

SMILES Cc1cccc(Cl)c1Nc1nc2ccc(cc2n2cncc12)C#N

InChI Key InChIKey=NLWQEFDCZXNPDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120096   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120096(4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]quin...)
Affinity DataIC50: 100nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120096(4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]quin...)
Affinity DataIC50: 100nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed