BDBM50120120 (2,6-Dimethyl-phenyl)-(9-nitro-imidazo[1,5-a]quinoxalin-4-yl)-amine::4-(2,6-Dimethyl-phenylamino)-5-nitro-imidazo[1,5-a]quinoxalin-5-ium::CHEMBL323059::N-(2,6-dimethylphenyl)-9-nitroimidazo[1,5-a]quinoxalin-4-amine

SMILES Cc1cccc(C)c1Nc1nc2cccc([N+]([O-])=O)c2n2cncc12

InChI Key InChIKey=WZXOJGDWGFMVGO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50120120   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120120(N-(2,6-dimethylphenyl)-9-nitroimidazo[1,5-a]quinox...)
Affinity DataIC50: 100nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120120(N-(2,6-dimethylphenyl)-9-nitroimidazo[1,5-a]quinox...)
Affinity DataIC50: 100nMAssay Description:Evaluated for inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120120(N-(2,6-dimethylphenyl)-9-nitroimidazo[1,5-a]quinox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed