BDBM50120144 C-{(S)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-hexyl)-azetidin-2-yl]}-methylamine::CHEMBL106084

SMILES CCCCCC(N1CC[C@H]1[C@@H](N)c1cccc(Cl)c1)c1ccccc1

InChI Key InChIKey=JQEVLYWMVMKITJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120144   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120144(C-{(S)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-hexy...)
Affinity DataKi:  772nMAssay Description:Compound was evaluated for increase in [35S]GTP-gamma-S, binding for human ORL1 receptor carried out in CHO cell membranes; Nd: no dataMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120144(C-{(S)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-hexy...)
Affinity DataKi:  2.15E+3nMAssay Description:Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120144(C-{(S)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-hexy...)
Affinity DataKi:  3.91E+3nMAssay Description:Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120144(C-{(S)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-hexy...)
Affinity DataKi:  7.58E+3nMAssay Description:Binding affinity at human opioid receptor delta 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed