BDBM50120153 C-((S)-C-(3-Chloro-phenyl)-C-{(S)-1-[1-(3-fluoro-phenyl)-pentyl]-azetidin-2-yl})-methylamine::CHEMBL106190

SMILES CCCCC(N1CC[C@H]1[C@@H](N)c1cccc(Cl)c1)c1cccc(F)c1

InChI Key InChIKey=IUNNNLPJQWHQNA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120153   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120153(C-((S)-C-(3-Chloro-phenyl)-C-{(S)-1-[1-(3-fluoro-p...)
Affinity DataKi:  680nMAssay Description:Compound was evaluated for increase in [35S]GTP-gamma-S, binding for human ORL1 receptor carried out in CHO cell membranes; Nd: no dataMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120153(C-((S)-C-(3-Chloro-phenyl)-C-{(S)-1-[1-(3-fluoro-p...)
Affinity DataKi:  4.13E+3nMAssay Description:Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120153(C-((S)-C-(3-Chloro-phenyl)-C-{(S)-1-[1-(3-fluoro-p...)
Affinity DataKi:  4.71E+3nMAssay Description:Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120153(C-((S)-C-(3-Chloro-phenyl)-C-{(S)-1-[1-(3-fluoro-p...)
Affinity DataKi:  1.23E+4nMAssay Description:Binding affinity at human opioid receptor delta 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed