BDBM50120336 CHEMBL3616684

SMILES CC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2ccc(cc2)C#N)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=YCVPCBGWUSVMHP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120336   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50120336(CHEMBL3616684)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50120336(CHEMBL3616684)
Affinity DataIC50: 43nMAssay Description:Antagonist activity against human glucagon receptor expressed in CHO cells assessed as reduction in glucagon-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed