BDBM50120454 CHEMBL3617977

SMILES COC(=O)C1=C(C)N(c2n[nH]c(=O)n2[C@@H]1c1ccc(cc1CCCN(C)C)C#N)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=LRTMFXXHBKWDDL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50120454   

TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120454(CHEMBL3617977)
Affinity DataIC50: 20nMAssay Description:Inhibition of human neutrophil elastase using MeO-Succ-Ala-Ala-Pro-Val-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed