BDBM50120543 7-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-imidazo[1,2-a]pyridine::CHEMBL49532

SMILES Cc1ccn2cc(nc2c1)-c1ccc(OCCCN2CCCCC2)cc1

InChI Key InChIKey=HHZLKORDNNRTRS-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50120543   

TargetHistamine H3 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50120543(7-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  2nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50120543(7-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  2nMAssay Description:Binding affinity towards human Histamine H3 receptor using [3H]N-methyl-histamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50120543(7-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  2nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma-S-AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50120543(7-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50120543(7-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  2nMAssay Description:Inhibition of H3R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50120543(7-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  2nMAssay Description:Inhibition of H3R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50120543(7-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  10nMAssay Description:Compound was tested for its binding affinity for rat histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed