BDBM50120938 (8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-chloro-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6-yl)-amine::CHEMBL148353

SMILES Clc1ccc2Nc3ncccc3N=C(NC3CC4CCC(C3)N4Cc3ccccc3)c2c1

InChI Key InChIKey=JQCALUODVNXQRL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50120938   

Target5-hydroxytryptamine receptor 2A(Rat)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50120938((8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-chloro-...)
Affinity DataKi:  36nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50120938((8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-chloro-...)
Affinity DataKi:  115nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50120938((8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-chloro-...)
Affinity DataKi:  136nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed