BDBM50120945 8-Chloro-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL436274

SMILES Clc1ccc2Nc3ncccc3N=C(N3CCN(CCc4ccccc4)CC3)c2c1

InChI Key InChIKey=OGHDWFXSMLKLNB-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50120945   

TargetD(4) dopamine receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50120945(8-Chloro-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[...)
Affinity DataKi:  40nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50120945(8-Chloro-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO-K1 cells assessed as inhibition constant measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50120945(8-Chloro-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[...)
Affinity DataKi:  103nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50120945(8-Chloro-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[...)
Affinity DataKi:  103nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50120945(8-Chloro-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[...)
Affinity DataKi:  892nMAssay Description:Displacement of [3H]-methylspiperone from human D2 receptor transfected in Sf9 cells assessed as inhibition constant measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50120945(8-Chloro-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[...)
Affinity DataKi:  892nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed