BDBM50120973 2,4-Diamino-7,8-dihydro-5H-1,3,6,9-tetraaza-anthracene-6-carboxylic acid benzyl ester::CHEMBL148599

SMILES Nc1nc(N)c2cc3CN(CCc3nc2n1)C(=O)OCc1ccccc1

InChI Key InChIKey=KNMOJBKUTVKLMX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120973   

TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50120973(2,4-Diamino-7,8-dihydro-5H-1,3,6,9-tetraaza-anthra...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against Escherichia coli (ec) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50120973(2,4-Diamino-7,8-dihydro-5H-1,3,6,9-tetraaza-anthra...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50120973(2,4-Diamino-7,8-dihydro-5H-1,3,6,9-tetraaza-anthra...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory activity against Toxoplasma gondii (tg) Dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50120973(2,4-Diamino-7,8-dihydro-5H-1,3,6,9-tetraaza-anthra...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against recombinant human Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed