BDBM50120978 6-(3,4-Dichloro-benzyl)-5,6,7,8-tetrahydro-1,3,6,9-tetraaza-anthracene-2,4-diamine::CHEMBL439816

SMILES Nc1nc(N)c2cc3CN(Cc4ccc(Cl)c(Cl)c4)CCc3nc2n1

InChI Key InChIKey=CIMZNQGMRUUJFW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120978   

TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50120978(6-(3,4-Dichloro-benzyl)-5,6,7,8-tetrahydro-1,3,6,9...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against Escherichia coli (ec) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50120978(6-(3,4-Dichloro-benzyl)-5,6,7,8-tetrahydro-1,3,6,9...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50120978(6-(3,4-Dichloro-benzyl)-5,6,7,8-tetrahydro-1,3,6,9...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity against Toxoplasma gondii (tg) Dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50120978(6-(3,4-Dichloro-benzyl)-5,6,7,8-tetrahydro-1,3,6,9...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibitory activity against recombinant human Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed