BDBM50120983 CHEMBL115136::[(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl)-2-methyl-propyl]-carbamic acid tert-butyl ester

SMILES CC[C@@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)N(C(C)=O)C1=O

InChI Key InChIKey=WSTYSIWMSQMTSY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120983   

TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983([(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethyl-5-oxo-hexahyd...)
Affinity DataIC50: 4.47E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 h pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983([(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethyl-5-oxo-hexahyd...)
Affinity DataIC50: 1.47E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983([(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethyl-5-oxo-hexahyd...)
Affinity DataIC50: 2.16E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983([(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethyl-5-oxo-hexahyd...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed