BDBM50121158 5'-(3-chlorophenyl)spiro[cyclopentane-1,3'-indol]-2'(1'H)-one::CHEMBL118963

SMILES Clc1cccc(c1)-c1ccc2NC(=O)C3(CCCC3)c2c1

InChI Key InChIKey=KPIHZVGWIFJTAZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121158   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121158(5'-(3-chlorophenyl)spiro[cyclopentane-1,3'-indol]-...)
Affinity DataIC50: 32nMAssay Description:Inhibition of 3 nM [3H]R5020 binding to progesterone receptor of human T47D cell cytosolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121158(5'-(3-chlorophenyl)spiro[cyclopentane-1,3'-indol]-...)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at progesterone receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed