BDBM50121312 Ac-Arg-D-Cha-I2aa-D-Arg-D-pClPhe-NH2::CHEMBL266609

SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@H]1CC[C@H]2SC[C@H](N2C1=O)C(=O)N[C@H](CCCNC(N)=N)C(=O)NC(Cc1ccc(Cl)cc1)C(N)=O

InChI Key InChIKey=TVMPRXGFXMXJRH-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50121312   

TargetNociceptin receptor(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50121312(Ac-Arg-D-Cha-I2aa-D-Arg-D-pClPhe-NH2 | CHEMBL26660...)
Affinity DataKi:  44nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding against human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50121312(Ac-Arg-D-Cha-I2aa-D-Arg-D-pClPhe-NH2 | CHEMBL26660...)
Affinity DataKi:  75nMAssay Description:Binding affinity for opioid receptor type, human Opioid receptor mu 1 expressed in membrane homogenates of COS-1 or CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50121312(Ac-Arg-D-Cha-I2aa-D-Arg-D-pClPhe-NH2 | CHEMBL26660...)
Affinity DataKi:  190nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding using COS-human Opioid receptor kappa 1 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50121312(Ac-Arg-D-Cha-I2aa-D-Arg-D-pClPhe-NH2 | CHEMBL26660...)
Affinity DataEC50: >1.00E+3nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding using COS-human Opioid receptor kappa 1 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50121312(Ac-Arg-D-Cha-I2aa-D-Arg-D-pClPhe-NH2 | CHEMBL26660...)
Affinity DataEC50:  1.40E+3nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding using COS-human Opioid receptor mu 1 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50121312(Ac-Arg-D-Cha-I2aa-D-Arg-D-pClPhe-NH2 | CHEMBL26660...)
Affinity DataKi:  5.20E+3nMAssay Description:Binding affinity for opioid receptor type, human Opioid receptor delta 1 expressed in membrane homogenates of COS-1 or CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed