BDBM50121387 CHEMBL3622141

SMILES CNc1nc2n(C[C@H](O)CO)c(cc2c2n(C)cnc12)C(=O)N(C)C1CC1

InChI Key InChIKey=OGLUSXCKVSEGPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121387   

TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50121387(CHEMBL3622141)
Affinity DataIC50: 450nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50121387(CHEMBL3622141)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed