BDBM50121633 4-[2-(4-{[3-(2-Chloro-phenyl)-propyl]-methyl-amino}-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino)-ethyl]-phenol::CHEMBL346215

SMILES CN(CCCc1ccccc1Cl)c1nc(NCCc2ccc(O)cc2)nc(n1)N1CCNCC1

InChI Key InChIKey=XWMDKLJFXDGCDU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121633   

TargetEstrogen receptor beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50121633(4-[2-(4-{[3-(2-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  40nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50121633(4-[2-(4-{[3-(2-Chloro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  680nMAssay Description:In vitro binding affinity towards human Estrogen receptor alpha using [3H]17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed