BDBM50121900 Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pro-Val-NH2::CHEMBL439490

SMILES CCCC[C@H](NC(=O)C(CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C(C)C)C(N)=O

InChI Key InChIKey=UAHFGYDRQSXQEB-UHFFFAOYSA-N

Data  13 KI  1 IC50  58 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 72 hits for monomerid = 50121900   

TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.00800nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0140nMAssay Description:Agonistic activity against mouse MC1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0180nMAssay Description:Effective concentration for mouse Melanocortin-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0230nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells by beta-galactosidase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0300nMAssay Description:Functional activity at the mouse melanocortin 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0320nMAssay Description:In vitro agonist potency for Mouse Melanocortin 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0380nMAssay Description:Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0380nMAssay Description:In vitro activation of mouse recombinant Melanocortin-1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0380nMAssay Description:Agonist activity to the mouse Melanocortin-1 receptor (mMC1R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0500nMAssay Description:Agonist activity at mouse MC1 receptor expressed in HEK293 cells after 6 hrs by cAMP-based beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0620nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0630nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0700nMAssay Description:In vitro agonist potency for Mouse Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0710nMAssay Description:Agonist activity towards mouse Melanocortin-5 receptor (mMC5R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0710nMAssay Description:Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0710nMAssay Description:Effective concentration against mouse Melanocortin 5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0710nMAssay Description:In vitro activation of mouse recombinant Melanocortin-5 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0780nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0780nMAssay Description:In vitro agonist potency for Mouse Melanocortin 5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0850nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells by beta-galactosidase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0860nMAssay Description:Functional activity at the mouse melanocortin 5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0880nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells by CRE/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0890nMAssay Description:Effective concentration for mouse Melanocortin-3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0900nMAssay Description:Agonistic activity against mouse MC3RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0950nMAssay Description:Effective concentration for mouse Melanocortin-5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0970nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0980nMAssay Description:Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0980nMAssay Description:Effective concentration against mouse Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0980nMAssay Description:Agonist activity to the mouse Melanocortin-3 receptor (mMC3R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0980nMAssay Description:In vitro activation of mouse recombinant Melanocortin-3 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.100nMAssay Description:Functional activity at the mouse melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.120nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells by CRE/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells by beta-galactosidase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.140nMAssay Description:In vitro agonist potency for Mouse Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.140nMAssay Description:Agonistic activity against mouse MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.160nMAssay Description:Effective concentration for mouse Melanocortin-4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.170nMAssay Description:Agonistic activity against mouse MC5RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at mouse MC4 receptor expressed in HEK293 cells after 6 hrs by cAMP-based beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.210nMAssay Description:In vitro activation of mouse recombinant Melanocortin-4 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.210nMAssay Description:Effective concentration against mouse melanocortin MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity to the mouse Melanocortin-4 receptor (mMC4R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.210nMAssay Description:Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.230nMAssay Description:Agonist activity at mouse MC3 receptor expressed in HEK293 cells after 6 hrs by cAMP-based beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells by CRE/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at mouse MC5 receptor expressed in HEK293 cells after 6 hrs by cAMP-based beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.320nMAssay Description:Functional activity at the mouse melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.330nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells by CRE/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.380nMAssay Description:Effective concentration against mouse Melanocortin 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.510nMAssay Description:Agonist activity at the mutant MC4R F184A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataKi:  0.560nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R F184L expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 72 total ) | Next | Last >>