BDBM50122347 (S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-phenyl}-2-ethoxy-propionic acid::CHEMBL87307

SMILES [#6]-[#6]-[#8]-[#6@@H](-[#6]-c1ccc(-[#8]-[#6]\[#6]=[#6](\c2ccc(Br)cc2)-c2ccc(Br)cc2)cc1)-[#6](-[#8])=O

InChI Key InChIKey=BHXMKGICUPZZOO-UHFFFAOYSA-N

Data  15 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50122347   

LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  300nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  900nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  300nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  900nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  900nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor gamma (PPAR gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  300nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  400nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor delta (PPAR delta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  390nMAssay Description:Activity at human liver PPAR alpha expressed in HEK293 cells by PPAR-GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  540nMAssay Description:Activity at human placenta PPAR delta expressed in HEK293 cells by PPAR-GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  590nMAssay Description:Activity at human adipose tissue PPAR gamma expressed in HEK293 cells by PPAR-GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at GAL4 yeast DNA binding domain fused human PPARalpha LBD expressed in HEK293 cells co-expressing TK-MH100x4-Luc after 24 hrs by lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at GAL4 yeast DNA binding domain fused human PPARdelta LBD (128 end residues) expressed in HEK293 cells after 24 hrs by luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  900nMAssay Description:Agonist activity at GAL4N fused human PPARgamma LBD expressed in HEK293 cells co-expressing TK-MH100x4-Luc after 24 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMed
LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  302nMAssay Description:Transactivation of Homo sapiens (human) PPARalpha assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

LigandPNGBDBM50122347((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...)
Affinity DataEC50:  891nMAssay Description:Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article