BDBM50122374 1-(2,6-Dichloro-phenyl)-2-oxo-5-o-tolyl-1,2,3,4-tetrahydro-quinazoline-7-carboxylic acid methyl ester::CHEMBL94377::methyl 1-(2,6-dichlorophenyl)-2-oxo-5-o-tolyl-1,2,3,4-tetrahydroquinazoline-7-carboxylate

SMILES COC(=O)c1cc2N(C(=O)NCc2c(c1)-c1ccccc1C)c1c(Cl)cccc1Cl

InChI Key InChIKey=DCGZQHJFRDWHTA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50122374   

LigandPNGBDBM50122374(1-(2,6-Dichloro-phenyl)-2-oxo-5-o-tolyl-1,2,3,4-te...)
Affinity DataIC50: 11nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50122374(1-(2,6-Dichloro-phenyl)-2-oxo-5-o-tolyl-1,2,3,4-te...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50122374(1-(2,6-Dichloro-phenyl)-2-oxo-5-o-tolyl-1,2,3,4-te...)
Affinity DataIC50: 11nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed