BDBM50122402 1-(2,6-Dichloro-phenyl)-5-(2,4-difluoro-phenyl)-7-methoxy-3,4-dihydro-1H-quinazolin-2-one::1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-methoxy-3,4-dihydroquinazolin-2(1H)-one::CHEMBL96091

SMILES COc1cc2N(C(=O)NCc2c(c1)-c1ccc(F)cc1F)c1c(Cl)cccc1Cl

InChI Key InChIKey=FCDOVDMDLZRXCB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50122402   

TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122402(1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-me...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122402(1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-me...)
Affinity DataIC50: 11nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122402(1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-me...)
Affinity DataIC50: 11nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article