BDBM50122474 3-{1-[2,5-Dioxo-1-(2'-sulfamoyl-biphenyl-4-yl)-pyrrolidin-(3Z)-ylidene]-ethyl}-benzamidine::CHEMBL99629

SMILES NC(=N)c1cccc(c1)C(=C)c1cc(O)n(c1O)-c1ccc(cc1)-c1ccccc1S(N)(=O)=O

InChI Key InChIKey=VYWWVEJABLTNFO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50122474   

TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122474(3-{1-[2,5-Dioxo-1-(2'-sulfamoyl-biphenyl-4-yl)-pyr...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration to coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122474(3-{1-[2,5-Dioxo-1-(2'-sulfamoyl-biphenyl-4-yl)-pyr...)
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration required against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122474(3-{1-[2,5-Dioxo-1-(2'-sulfamoyl-biphenyl-4-yl)-pyr...)
Affinity DataIC50: 670nMAssay Description:Inhibitory concentration required against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed