BDBM50122882 4-(1-{1-[2-(2-Chloro-phenyl)-ethylcarbamoyl]-2-mercapto-ethylcarbamoyl}-3-methyl-butylcarbamoyl)-4-isobutoxycarbonylamino-butyric acid::CHEMBL117815

SMILES CC(C)C[C@H](NC(=O)C(CCC(O)=O)NC(=O)OC(C)(C)C)C(=O)NC(CC(F)F)C(=O)NCCc1ccccc1Cl

InChI Key InChIKey=OPACFFJINGAWIU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50122882   

TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122882(4-(1-{1-[2-(2-Chloro-phenyl)-ethylcarbamoyl]-2-mer...)
Affinity DataKi:  7.30E+3nMAssay Description:Binding affinity for enzyme NS3 protease wild-typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122882(4-(1-{1-[2-(2-Chloro-phenyl)-ethylcarbamoyl]-2-mer...)
Affinity DataKi:  8.30E+3nMAssay Description:Binding affinity for enzyme K136RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122882(4-(1-{1-[2-(2-Chloro-phenyl)-ethylcarbamoyl]-2-mer...)
Affinity DataKi:  1.35E+4nMAssay Description:Binding affinity for enzyme K136MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122882(4-(1-{1-[2-(2-Chloro-phenyl)-ethylcarbamoyl]-2-mer...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for enzyme human leukocyte HLEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed