BDBM50122994 2-(4-Fluoro-phenyl)-3-pyridin-4-yl-imidazo[1,2-a]pyrimidin-7-ylamine::CHEMBL119648

SMILES Nc1ccn2c(c(nc2n1)-c1ccc(F)cc1)-c1ccncc1

InChI Key InChIKey=SXRLSMDAMBCWBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50122994   

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50122994(2-(4-Fluoro-phenyl)-3-pyridin-4-yl-imidazo[1,2-a]p...)
Affinity DataIC50: 40nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50122994(2-(4-Fluoro-phenyl)-3-pyridin-4-yl-imidazo[1,2-a]p...)
Affinity DataIC50: 570nMAssay Description:Inhibition of murine p38 alpha kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed