BDBM50123047 2-{3-Chloro-4-[4-hydroxy-3-(4-methyl-piperazine-1-sulfonyl)-phenoxy]-5-methyl-phenyl}-2H-[1,2,4]triazine-3,5-dione::CHEMBL127338

SMILES CN1CCN(CC1)S(=O)(=O)c1cc(Oc2c(C)cc(cc2Cl)-n2ncc(=O)[nH]c2=O)ccc1O

InChI Key InChIKey=DAJCENZLWJTVJS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123047   

TargetThyroid hormone receptor beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50123047(2-{3-Chloro-4-[4-hydroxy-3-(4-methyl-piperazine-1-...)
Affinity DataKi:  13nMAssay Description:Effective concentration binding towards TR-beta-1 in E25B2 cells (agonistic activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed