BDBM50123084 2-{3-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-isoindole-1,3-dione::CHEMBL334956

SMILES Fc1ccc2[nH]cc(C3=CCN(CCCN4C(=O)c5ccccc5C4=O)CC3)c2c1

InChI Key InChIKey=MKIPKEANVGLYQX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123084   

TargetD(2) dopamine receptor(Human)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50123084(2-{3-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-py...)
Affinity DataKi:  20nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50123084(2-{3-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-py...)
Affinity DataKi:  25nMAssay Description:In vitro binding affinity for serotonin reuptake sites in rat frontal cortex membranes by [3H]paroxetine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed