BDBM50123251 (S)-2-Benzenesulfonylamino-3-{[5-(2-guanidinomethyl-phenyl)-thiophene-2-carbonyl]-amino}-propionic acid; TFA::CHEMBL357486

SMILES [#7]\[#6](-[#7])=[#7]/[#6]-c1ccccc1-c1ccc(s1)-[#6](=O)-[#7]-[#6]-[#6@H](-[#7]S(=O)(=O)c1ccccc1)-[#6](-[#8])=O

InChI Key InChIKey=BPBHTITUTUZWBT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50123251   

TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123251((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidinomethy...)
Affinity DataIC50: 21nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alphaV-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123251((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidinomethy...)
Affinity DataIC50: 0.00580nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123251((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidinomethy...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of vitronectin binding to HT-29 cells expressing integrin alphaV-beta5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123251((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidinomethy...)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of fibrinogen binding to integrin alphaV-beta3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed