BDBM50123455 CHEMBL3621496

SMILES CN1CCN(CC1)C(=O)c1ccc2c(c1)[nH]c1c(ccc(-c3ccccc3F)c21)C(N)=O

InChI Key InChIKey=SDVAHCXGDGYWFA-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50123455   

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123455(CHEMBL3621496)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant BTKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123455(CHEMBL3621496)
Affinity DataIC50: 39nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123455(CHEMBL3621496)
Affinity DataIC50: 41nMAssay Description:Inhibition of cKIT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123455(CHEMBL3621496)
Affinity DataIC50: 50nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123455(CHEMBL3621496)
Affinity DataIC50: 68nMAssay Description:Inhibition of LYNa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123455(CHEMBL3621496)
Affinity DataIC50: 81nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123455(CHEMBL3621496)
Affinity DataIC50: 116nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2016
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123455(CHEMBL3621496)
Affinity DataIC50: 119nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase TXK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123455(CHEMBL3621496)
Affinity DataIC50: 119nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2016
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123455(CHEMBL3621496)
Affinity DataIC50: 444nMAssay Description:Inhibition of Aurora-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123455(CHEMBL3621496)
Affinity DataIC50: 610nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2016
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123455(CHEMBL3621496)
Affinity DataIC50: 753nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2016
Entry Details Article
PubMed