BDBM50123488 2-[3-(2,2-Difluoro-2-phenyl-ethylamino)-6-methyl-2-oxo-2H-pyrazin-1-yl]-N-(3-fluoro-pyridin-2-ylmethyl)-acetamide::CHEMBL143879

SMILES Cc1cnc(NCC(F)(F)c2ccccc2)c(=O)n1CC(=O)NCc1ncccc1F

InChI Key InChIKey=UPYFICZRANWLAQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123488   

TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123488(2-[3-(2,2-Difluoro-2-phenyl-ethylamino)-6-methyl-2...)
Affinity DataKi:  6.80nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123488(2-[3-(2,2-Difluoro-2-phenyl-ethylamino)-6-methyl-2...)
Affinity DataKi:  5.01E+5nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed