BDBM50123489 2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl)-N-pyridin-2-ylmethyl-acetamide::CHEMBL143060

SMILES Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccccn1

InChI Key InChIKey=IOTXWKCEEOXTJU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123489   

TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123489(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi:  390nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123489(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed