BDBM50123506 2-[6-Chloro-3-(2,2-difluoro-2-pyridin-2-yl-ethylamino)-2-oxo-2H-pyrazin-1-yl]-N-(3-methoxy-pyridin-2-ylmethyl)-acetamide::CHEMBL342994

SMILES COc1cccnc1CNC(=O)Cn1c(Cl)cnc(NCC(F)(F)c2ccccn2)c1=O

InChI Key InChIKey=OEHPWTVUGZGFLF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123506   

TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123506(2-[6-Chloro-3-(2,2-difluoro-2-pyridin-2-yl-ethylam...)
Affinity DataKi:  15nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123506(2-[6-Chloro-3-(2,2-difluoro-2-pyridin-2-yl-ethylam...)
Affinity DataKi:  7.06E+5nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed