BDBM50123508 CHEMBL148159::[2'-(2-Pyridin-2-yl-ethylcarbamoyl)-biphenyl-2-ylmethyl]-carbamic acid benzyl ester

SMILES O=C(NCc1ccccc1-c1ccccc1C(=O)NCCc1ccccn1)OCc1ccccc1

InChI Key InChIKey=FLOLVFLAXFXKBU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50123508   

TargetPotassium voltage-gated channel subfamily A member 5(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50123508([2'-(2-Pyridin-2-yl-ethylcarbamoyl)-biphenyl-2-ylm...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human voltage-gated potassium channel subunit Kv1.5 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50123508([2'-(2-Pyridin-2-yl-ethylcarbamoyl)-biphenyl-2-ylm...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human voltage-gated potassium channel subunit Kv1.3 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123508([2'-(2-Pyridin-2-yl-ethylcarbamoyl)-biphenyl-2-ylm...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123508([2'-(2-Pyridin-2-yl-ethylcarbamoyl)-biphenyl-2-ylm...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human TASK-1 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at +40mV holding potential by two-electrode ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed