BDBM50123754 (E)-(1S,2S,6S,7R)-2,6-Dihydroxy-1-(4-hydroxy-2,6-dimethyl-benzyl)-7-phenethyloxycarbonyl-8-phenyl-oct-4-enyl-ammonium

SMILES Cc1cc(O)cc(C)c1C[C@H]([NH3+])[C@@H](O)C\C=C\[C@H](O)[C@@H](Cc1ccccc1)C(=O)OCCc1ccccc1

InChI Key InChIKey=FWZKNXOQDVISEU-UHFFFAOYSA-O

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50123754   

TargetMu-type opioid receptor(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123754((E)-(1S,2S,6S,7R)-2,6-Dihydroxy-1-(4-hydroxy-2,6-d...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123754((E)-(1S,2S,6S,7R)-2,6-Dihydroxy-1-(4-hydroxy-2,6-d...)
Affinity DataEC50:  4.20nMAssay Description:Compound tested at 10 uM for the ability to induce Opioid receptor mu 1-mediated binding of [35S]GTP-gamma-S to G proteins in CHO membrane preparatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123754((E)-(1S,2S,6S,7R)-2,6-Dihydroxy-1-(4-hydroxy-2,6-d...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]diprenorphine from human Opioid receptor delta 1 epressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123754((E)-(1S,2S,6S,7R)-2,6-Dihydroxy-1-(4-hydroxy-2,6-d...)
Affinity DataKi:  260nMAssay Description:Displacement of 3H-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellum preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed