BDBM50123768 4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1H-pyrrolo[3,2-b]pyridin-2-ylmethyl)-piperazin-2-one::CHEMBL160996

SMILES Clc1ccc2cc(sc2c1)S(=O)(=O)N1CCN(Cc2cc3ncccc3[nH]2)C(=O)C1

InChI Key InChIKey=SZWQUBUUZPTTEK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123768   

TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123768(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1H-py...)
Affinity DataKi: >1.20E+3nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123768(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1H-py...)
Affinity DataKi: >2.90E+3nMAssay Description:Binding affinity towards trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123768(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1H-py...)
Affinity DataKi: >3.90E+3nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed