BDBM50123772 4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1H-imidazo[4,5-c]pyridin-2-ylmethyl)-piperazin-2-one::CHEMBL162357

SMILES Clc1ccc2cc(sc2c1)S(=O)(=O)N1CCN(Cc2nc3ccncc3[nH]2)C(=O)C1

InChI Key InChIKey=JIKYTKHDQFAMNY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123772   

TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123772(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1H-im...)
Affinity DataKi: >1.20E+3nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123772(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1H-im...)
Affinity DataKi: >2.90E+3nMAssay Description:Binding affinity towards trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123772(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1H-im...)
Affinity DataKi: >3.90E+3nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed