BDBM50124116 2-(2-Chloro-pyridin-3-yl)-8-[(3,5-dichloro-pyridine-4-carbonyl)-amino]-3H-benzo[d][1,3]diazepine-4-carboxylic acid::CHEMBL166656

SMILES OC(=O)C1=NC(=Nc2cc(NC(=O)c3c(Cl)cncc3Cl)ccc2C1)c1cccnc1Cl

InChI Key InChIKey=GEUBEALHFRYOQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124116   

TargetIntegrin alpha-4/beta-1(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124116(2-(2-Chloro-pyridin-3-yl)-8-[(3,5-dichloro-pyridin...)
Affinity DataIC50: 55nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124116(2-(2-Chloro-pyridin-3-yl)-8-[(3,5-dichloro-pyridin...)
Affinity DataIC50: 410nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed