BDBM50124129 CHEMBL3622224

SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1cccc2ccccc12)c1cccc(I)c1

InChI Key InChIKey=JOXOSYLMICYIJG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124129   

Target72 kDa type IV collagenase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50124129(CHEMBL3622224)
Affinity DataIC50: 9.33E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50124129(CHEMBL3622224)
Affinity DataIC50: 9.43E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50124129(CHEMBL3622224)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of APMA-activated human recombinant MMP9 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed