BDBM50124433 5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide::CHEMBL367275

SMILES COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCNS(=O)(=O)c1cccs1)N1CCOCC1

InChI Key InChIKey=JGEXEIBPRHWMSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124433   

TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124433(5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-ph...)
Affinity DataIC50: 447nMAssay Description:Inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124433(5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-ph...)
Affinity DataIC50: 724nMAssay Description:Inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed