BDBM50124437 5-Methyl-pyridine-2-sulfonic acid [2-cyclopropyl-6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide::CHEMBL368528

SMILES CCS(=O)(=O)NCCOc1nc(nc(NS(=O)(=O)c2ccc(C)cn2)c1Oc1ccccc1OC)C1CC1

InChI Key InChIKey=VKVKIDBOTDIUCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124437   

TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124437(5-Methyl-pyridine-2-sulfonic acid [2-cyclopropyl-6...)
Affinity DataIC50: 582nMAssay Description:Inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124437(5-Methyl-pyridine-2-sulfonic acid [2-cyclopropyl-6...)
Affinity DataIC50: 5.66E+3nMAssay Description:Inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed