BDBM50124613 5-Allyl-9,10-dimethoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL274208

SMILES COc1ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c2c1OC

InChI Key InChIKey=RLNRYNADPTVFSB-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124613   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50124613(5-Allyl-9,10-dimethoxy-2,2,4-trimethyl-2,5-dihydro...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]dexamethasone as radioligand in SF-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50124613(5-Allyl-9,10-dimethoxy-2,2,4-trimethyl-2,5-dihydro...)
Affinity DataEC50:  120nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50124613(5-Allyl-9,10-dimethoxy-2,2,4-trimethyl-2,5-dihydro...)
Affinity DataKi:  610nMAssay Description:Displacement of [3H]progesterone from human Progesterone receptor AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed