BDBM50124687 2-Benzyl-5-(4-methanesulfonyl-phenyl)-4-(6-methyl-pyridin-3-yl)-2H-pyridazin-3-one::CHEMBL155587

SMILES Cc1ccc(cn1)-c1c(cnn(Cc2ccccc2)c1=O)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=HWLOTFLJLWOMHZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124687   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50124687(2-Benzyl-5-(4-methanesulfonyl-phenyl)-4-(6-methyl-...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 stably transfected in Human whole blood (HWB) cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50124687(2-Benzyl-5-(4-methanesulfonyl-phenyl)-4-(6-methyl-...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 stably transfected in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50124687(2-Benzyl-5-(4-methanesulfonyl-phenyl)-4-(6-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against sensitive U-937 microsomal prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed