BDBM50124726 2-(2,6-Dichloro-benzylsulfanyl)-6-formyl-nicotinonitrile::CHEMBL160642

SMILES Clc1cccc(Cl)c1CSc1nc(C=O)ccc1C#N

InChI Key InChIKey=ZIMDDBUYLJSPMR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124726   

TargetTelomerase reverse transcriptase(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50124726(2-(2,6-Dichloro-benzylsulfanyl)-6-formyl-nicotinon...)
Affinity DataIC50: 7.00E+3nMAssay Description:In vitro inhibitory activity of compound against telomerase (Acc Gerons data)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50124726(2-(2,6-Dichloro-benzylsulfanyl)-6-formyl-nicotinon...)
Affinity DataIC50: 7.70E+4nMAssay Description:In vitro inhibitory activity of compound against telomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50124726(2-(2,6-Dichloro-benzylsulfanyl)-6-formyl-nicotinon...)
Affinity DataIC50: 1.13E+5nMAssay Description:In vitro antiproliferative activity of compound against HT-29 (human colon caner ) cell line was determined by SRB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed