BDBM50124779 (S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(3-trifluoromethyl-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::CHEMBL158471

SMILES CCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cccc(c1)C(F)(F)F)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O

InChI Key InChIKey=YMJROSIKZXDPLB-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50124779   

TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124779((S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataEC50:  45nMAssay Description:Effective concentration against hMC4R using HEK293 cells was determined by measuring cAMP accumulation at 50 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124779((S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124779((S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataEC50:  611nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124779((S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibitory concentration of compound was determined against hMC1R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed