BDBM50125100 Biphenyl-2-carboxylic acid [3-chloro-4-(1,3,4,5-tetrahydro-azepino[4,3,2-cd]indole-6-carbonyl)-phenyl]-amide::CHEMBL166261

SMILES Clc1cc(NC(=O)c2ccccc2-c2ccccc2)ccc1C(=O)N1CCCc2c[nH]c3cccc1c23

InChI Key InChIKey=XKAHJYAAQXISCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125100   

TargetVasopressin V2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125100(Biphenyl-2-carboxylic acid [3-chloro-4-(1,3,4,5-te...)
Affinity DataIC50: 330nMAssay Description:Inhibitory activity of the human V2 receptor was assessed by the accumulation of cAMP in transfected HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125100(Biphenyl-2-carboxylic acid [3-chloro-4-(1,3,4,5-te...)
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]AVP from human V2 receptors expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed