BDBM50125132 ((R)-1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-beta-carbolin-2-yl)-[5-(4-chloro-2-nitro-phenyl)-furan-2-yl]-methanone::CHEMBL164173

SMILES [O-][N+](=O)c1cc(Cl)ccc1-c1ccc(o1)C(=O)N1CCc2c([nH]c3ccccc23)[C@H]1c1ccc2OCOc2c1

InChI Key InChIKey=BFFZFBPUOMXAPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125132   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125132(((R)-1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-be...)
Affinity DataIC50: 67nMAssay Description:Inhibition of PDE5 (Phosphodiesterase) from human corpus cavernosumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125132(((R)-1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-be...)
Affinity DataIC50: 67nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed