BDBM50125142 CHEMBL349204::N-{4-[5-(1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-beta-carboline-2-carbonyl)-furan-2-yl]-phenyl}-acetamide

SMILES CC(=O)Nc1ccc(cc1)-c1ccc(o1)C(=O)N1CCc2c([nH]c3ccccc23)C1c1ccc2OCOc2c1

InChI Key InChIKey=CESZVDFKPQPIGI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125142   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125142(N-{4-[5-(1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydr...)
Affinity DataKi:  64nMAssay Description:Inhibitory activity against PDE5 from human corpus cavernosumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125142(N-{4-[5-(1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydr...)
Affinity DataKi:  64nMAssay Description:Binding affinity to PDE5 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed